Building Blocks

  1. Norbornenes – Will You Click Me?

    Proposing norbornenes – strained, bicyclic alkenes for fast, copper-free, biocompatible click-conjugation with tetrazines. Read on for more details on applications and available products!

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  2. PotM: About the Impact of Fluorinated Building Blocks

    Clever Move - Add positive effects to your molecule by introducing the most electronegative element. Discover fluorinated building blocks as game changer for your lead development. 

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  3. Carboxymethyl Amino Acid Derivatives

    Level up! Carboxymethyl-modified amino acid building blocks suitable for incorporation by solid-phase peptide synthesis. Learn more about available derivatives and their properties.

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  4. Azobenzene Photoswitches

    Engineer shape-shifting peptides, controllable by a laser as magic wand! In this newsletter, we’ll explore the possibilities of photo switchable building blocks based on azobenzene.

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  5. PotM: Oligomeric Sarcosine Building Blocks

    You are looking for monodisperse Sarcosines? You want to use Sarcosine for SPPS? You need to improve your drug's hydrophilicity and search for PEG alternatives? Read on!

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  6. Fluorogenic Building Blocks for Peptide Guided Wash-Free Imaging

    Live-imaging of dynamic structures and catching events in living cells is a challenge, as most fluorescent probes have a high background signal. For alternatives, please read on!

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  7. PotM: Blockbuster Building Blocks

    Are you keen on developing novel billion-dollar-selling peptide API blockbusters? Most recent ones use lipophilic Albumin binding moieties. Of course, Iris Biotech has the necessary building blocks!

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  8. A Tetrazole-Substituted Lysine as PTM Isostere

    The tetrazole isostere of malonyllysine is thermally stable and does not suffer from decarboxylation. Discover our building blocks suitable for incorporation via solid-phase peptide synthesis.

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  9. Glycosylated Asparagine Building Blocks for SPPS

    Add glycans to your proteins with our ready-to-use Fmoc asparagine building blocks suitable for solid phase peptide synthesis and produce peptides with exactly defined glycosylation patterns!

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  10. Automated Peptide Synthesis

    The discovery of the Merrifield peptide synthesis paved the way for automated solid-phase peptide synthesis (SPPS) enabling fast and convenient simultaneous peptide synthesis.

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