Blog

  1. PotM: Furan-Crosslinking and 5HP2O as Maleimide Alternative

    Game Changer for Protein Modification: Discover oxidation-induced furan crosslinking and 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones (5HP2Os) as stable alternative to maleimides.

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  2. Workshop: About Furan and a Maleimide Replacement Technology

    60-minute online workshop “About Furan and a Maleimide Replacement Technology” on December 4th at 3 pm CET featuring Prof. Dr. Annemieke Madder, Universiteit Gent. Save the date and join us!

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  3. A Fluorescent Probe for “Hard and Soft” Reactive Metabolites

    Discover CysGluDan, a new fluorescent probe for the detection of reactive metabolites in drug development, which can detect both "soft" and "hard" nucleophiles. 

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  4. Chain Extension: Discover Homo Amino Acids

    We expanded our portfolio of Fmoc-protected homo amino acids. Benefit of their unique properties to modulate the stability, hydrophobicity, and biological performance of your peptide!

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  5. HMPO: A pH-Responsive Linker for Targeted Drug Delivery

    HMPO (5-(hydroxymethyl)pyrogallol orthoester), a plasma-stable, pH-sensitive, 1,6-self-immolative crosslinker derived from the natural product gallic acid. Discover its properties!

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  6. PotM: MYTsA – A Novel Ynamide Coupling Reagent

    Discover MYTsA as coupling reagent for peptide synthesis in “traditional” C→N and vice versa in “natural” N→C direction. Avoid racemization and benefit of improved atom economy!

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  7. Workshop: The Chemistry behind how life startet on Earth

    You missed our Workshop with Prof. Thomas Carell? As unpublished data was shown, the recording of the workshop will just be available on our homepage in a few weeks. If you would like to be informed please get in contact via info@iris-biotech.de.

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