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News
Visit this regularly updated section to check out the latest additions to our portfolio, as well as the latest developments at Iris Biotech.
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Betulins – Potent Natural Products
Betulin and its derivatives are pentacyclic triterpenoids of the lupane-type. They are natural products that occur as secondary metabolites in over 200 different plants. Betulinic acid (BA) is a derivative of betulin that is oxidized at C-28.
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YRFM: Best Flash Communication Award
At the Young Researcher Fellow Meeting (YRFM) 2020 Iris Biotech had the honor to sponsor the award "Best Flash Communication Award".
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Congratulations to Mirjana Antonijevic and Martha Hernandez Carrillo.
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Cleavable Bifunctional Biotin-Linkers
Biotinylation of proteins and their purification via Streptavidin beads is a widely applied method.
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Product of the Month: Biotin-Aniline for Proximity Labeling of RNA
Proximity labeling of proteins with biotin-phenol (biotin-tyramide) and an engineered peroxidase enzyme (e.g. APEX = Engineered Ascorbate Peroxidase) is a pivotal tool for molecular biology.
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Product of the Month: Fmoc-L-Cys(Allocam)-OH for 1-Step On-Resin Disulfide Bond Formation
The Allocam protecting group allows for selective deprotection and disulfide bond formation on-resin in one step.
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Diazirine Amino Acids: Photocrosslinking Applications
Two selected publications were summarized in this article in order to highlight the impressive utility of amino acids incorporating the diazirine photophore.
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Protease Inhibitors
Protease inhibitors are molecules that inhibit protease function by binding either reversibly or irreversibly to the enzyme.
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Membrane-Impermeant Biotin Tyramide
Methods for proteomic mapping of cellular organelles or subdomains that avoid the necessity of cell lysis and purification by targeting specific subcellular regions have several advantages.
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