1. Tougher Restrictions on DMF

    REACH regulation for the handling of N,N-dimethylformamide (DMF), the most commonly used solvent for solid-phase peptide synthesis (SPPS). Read more about consequences and alternatives!

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  2. PotM: TCEP as Versatile Reducing Agent

    TCEP is an effective reductant for disulfide bonds and a versatile reagent for various applications in protein science with distinct advantages compared to DTT and BME.

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  3. Coupling Reagents

    Coupling Reagents are required for the formation of an amide or ester bond. As simple as those reactions seem to be, the choice of the appropriate reagent is crucial for optimizing purity and yield.

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  4. Abraligabra - Reagents and Building Blocks for Chemical Ligation

    We can’t get enough of new products and innovations! Read this blog to get detailed information on the cyanylating reagent NTCB as well as selenocysteine amino acids, both useful tools for peptide ligation.

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  5. DTT and Spermidine for RNA Buffers and Vaccine Production

    See how our “mRNA grade” DTT and Spermidine can support also your nucleic acid production. Read on for more information.

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  6. Process Development of SPPS

    From mg synthesis of a peptide up to bulk quantities often makes a huge difference in the route of production. Read on for more information about Iris Biotech’s process development services.

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  7. PotM: 1,4-Benzenedimethanethiol (BDMT)

    1,4-Benzenedimethanethiol is used as thiol scavenger during solid-phase peptide synthesis. In comparison to other thiol scavengers, this reagent is odorless and provides high quality crude peptides.

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  8. Product of the Month: “Cleland’s Reagent” Dithiothreitol (DTT)

    DTT is a powerful yet mild reducing agent. Based on your demand we can offer different quality grades to suit your needs.

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  9. Fmoc-Amox, A Novel Reagent for Fmoc-Protection

    The most common reagent for the Fmoc-protection of amino acids is currently Fmoc-OSu, followed by Fmoc-Cl. However, the use of these reagents is usually accompanied by several side reactions, such as the formation of beta-alanine and dipeptides.

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  10. Fmoc Deprotection Reagents

    The Fmoc group is the most frequently used protecting group in peptide chemistry. The most common deprotection conditions involve a solution of 20% piperidine in DMF.

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