Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
USD
Quick contact
Please send me more information about
Fmoc-Aeg(Dde)-OH
Chemical name: (9-Fluorenylmethyloxycarbonyl)-N-(2-((1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl)amino)ethyl)glycine // Synonyms: Dde-Aeg(Fmoc), Fmoc-N-(2-Dde-aminoethyl)-glycine, Fmoc-N-(2-Dde-aminoethyl)-Gly-OH, Fmoc-N-(N-ß-Dde-aminoethyl)-Gly-OH,N-(((9H-fluoren-9-yl)methoxy)carbonyl)-N-(2-((1-(4,4-dimethyl-2,6-dioxocyclohex ylidene)ethyl)amino)ethyl)glycine, Fmoc-Aeg(Dde)
- Product code:FAA8690
- CAS No.:2988301-08-0
- Formula:C29H32N2O6
- Storage temperature:2-8°C
- Molecular weight:504.58 g/mol
- Purity :min. 98%
from $135.00
description
Building block for the preparation of protected PNA (Peptide Nucleic Acid) monomers. For selective Dde-cleavage please refer to this information: The best results in terms of reactivity and selectivity were achieved using a mixture of NH2OH*HCl/imidazole in NMP/CH2Cl2. After 3 h, the Dde group was cleaved cleanly while the Fmoc group was completely stable, yielding Dde-deprotected material as the only material with a quantitative yield.
This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis.
references
Full Orthogonality between Dde and Fmoc: The Direct Synthesis of PNA-Peptide Conjugates; J. J. Díaz-Mochón, L. Bialy, M. Bradley; Org. Lett. 2004, 6(7): 1127-1129; https://doi.org/10.1021/ol049905y
* Disclaimer
We refer to our general terms and conditions.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
Do you need further information about this product?
get in contact
Brochures & Flyers
We found other products you might like!
