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Boc-L-Ser[Psi(Me,Me)Pro]-OH
Chemical name: (S)-3-(tert-butoxycarbonyl)-2,2-dimethyloxazolidine-4-carboxylic acid // Synonyms: Boc-Ser[Psi(Me,Me)Pro]-OH
- Product code:PSI1630
- CAS No.:139009-66-8
- Formula:C11H19NO5
- Molecular weight:245.28 g/mol
- Purity :min. 99%
- Enantiomeric Purity:min. 99,7%
from $87.50
description
Serine-derived Pseudoproline monomer for SPPS. This building-block can be successfully coupled with many amino-acids using modern coupling techniques avoiding the need for pseudoproline dipeptides and giving the possibility to introduce pseudoprolines in peptides containing non-natural or rare amino-acids. See also the Fmoc-derivative FAA8590.
references
Reference:
Scope and limitations of pseudoprolines as individual amino acids in peptide synthesis; D. A. Senko, N. D. Timofeev, I. E. Kasheverov, I. A. Ivanov; Amino Acids 2021; 53: 665-671. https://doi.org/10.1007/s00726-021-02973-1.
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