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Visit this regularly updated section to check out the latest additions to our portfolio, as well as the latest developments at Iris Biotech.
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Protease Inhibitors
Protease inhibitors are molecules that inhibit protease function by binding either reversibly or irreversibly to the enzyme.
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Membrane-Impermeant Biotin Tyramide
Methods for proteomic mapping of cellular organelles or subdomains that avoid the necessity of cell lysis and purification by targeting specific subcellular regions have several advantages.
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Fmoc-L-Lys(Nvoc)-OH
o-Nitroveratryloxycarbonyl (Nvoc) is a photocleavable side chain protecting group for lysine that can be removed by irradiation with UV light (350 nm).
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H-L-Lys(Suc)-OH*HCl
Succinylation of proteins on the epsilon-amino group of lysine residues is a posttranslational modification that is still poorly understood.
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Amadori & Maillard reaction derived peptides
Find below derivatives of arginine and lysine bearing side chains as found in Maillard reaction products.
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(TPP-Lys(TPP))2-Lys-Gly-Gly-Gly-N2H3*4Br*TFA
Delivery of hydrophilic compounds across membranes is usually problematic. Modification with triphenylphosphonium ions has been shown to overcome this barrier.
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Product of the Month: Indocyanine Green (ICG) Dyes
Indocyanine Green (ICG) dye, a material approved by the FDA for various applications, is a powerful tool for imaging in live cells and tissues.
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A Cyclo-RGD Peptide for the Preparation of Tumor Mimics
The 2D monolayer cell culture model is widely applied for drug screening. However, this approach is frequently not able to adequately mimic the in vivo response.
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Hydrolysis-Stable Mimics of Phosphorylated Amino Acids (Ser, Thr and Tyr)
Phosphorylation of serine, threonine and tyrosine is counted among the most important posttranslational modifications that occur in organisms.
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