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(R,S)-Boc-2-Atc
Chemical name: 2-((tert-Butoxycarbonyl)amino)-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid // Synonyms: (R,S)-Boc-2-aminotetraline-2-carboxylic acid, 2-(Boc-amino)-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid, 2-[[(1,1-Dimethylethoxy)carbonyl]amino]-1,2,3,4-tetrahydro-2-naphthalenecarboxylic acid
- Product code:BAA4740
- CAS No.:98569-12-1
- Formula:C16H21NO4
- Storage temperature:2-8°C
- Molecular weight:291,35 g/mol
from €400.00
description
This derivative can be used as constrained phenylalanine building block for structure activity relationship studies. Such alpha,alpha-disubstituted amino acids are widely used in peptide design because of their structure promoting effects.
references
Conformational restriction of the phenylalanine residue in a cyclic opioid peptide analog: effects on receptor selectivity and stereospecificity; P. W. Schiller, G. Weltrowska, N. Tai Mai Dung, C. Lemieux, N. N. Chung, B. J. Marsden, B. C. Wilkes; J. Med. Chem. 1991; 34(10): 3125-3132. https://doi.org/10.1021/jm00114a023.
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