Amino Acids

  1. Fmoc-L-Lys(Nvoc)-OH

    o-Nitroveratryloxycarbonyl (Nvoc) is a photocleavable side chain protecting group for lysine that can be removed by irradiation with UV light (350 nm).

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  2. H-L-Lys(Suc)-OH*HCl

    Succinylation of proteins on the epsilon-amino group of lysine residues is a posttranslational modification that is still poorly understood.

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  3. Hydrolysis-Stable Mimics of Phosphorylated Amino Acids (Ser, Thr and Tyr)

    Phosphorylation of serine, threonine and tyrosine is counted among the most important posttranslational modifications that occur in organisms.

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  4. Diazirine Amino Acids for Photo Cross-Linkage in Living Cells

    Iris Biotech introduces a comprehensive set of photo-crosslinking amino acids bearing the diazirine moiety.

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  5. beta,beta-Dimethyl Amino Acids

    The use of bioactive peptides has increased over the recent years as they attracted attention for their use as therapeutic agents.

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  6. Fmoc-L-Cys(Propargyl)-OH

    This alkyne-functionalized cysteine building block can be incorporated into peptides via the Fmoc strategy.

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  7. Standard Fmoc Amino Acid Building Blocks

    Amino acids of high quality are crucial for the synthesis of peptides with a high purity.

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  8. Application of the Trt and Fmoc groups for the protection of polyfunctional α-amino acids

    Abstract: Ditrityl amino acids Trt-Lys(Trt)-OH (Trt = CPh3), Trt-Orn(Trt)-OH, Trt-Ser(Trt)-OH, and Trt-Hse(Trt)-OH were prepared and used in the synthesis of trityl-protected peptides, e.g., Trt-Ser(Trt)-Phe-NH2.

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  9. Triamino Acids

    Fmoc-L-Dap(2-Boc-aminoethyl)-OH is the first in a series of new triamino acid building blocks. This azalysine is useful for introducing positive charges into a peptide, or for creating branched structures.

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  10. Photocleavable NCL-Auxiliary Glycine

    This innovative auxiliary facilitates Native Chemical Ligation at the position of a Glycine residue in a peptide sequence. The auxiliary can be further functionalized, e.g. by PEGylation. Following NCL, the auxiliary is removed by irradiation with UV light.

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