Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
EUR
Quick contact
Please send me more information about
Fmoc-4-AMCHC-OH
Chemical name: trans-4-(9-Fluorenylmethyloxycarbonylaminomethyl)-cyclohexanoic acid // Synonyms: Fmoc-tranexamic acid, trans-4-(Fmoc-aminomethyl)cyclohexanecarboxylic acid, Fmoc-4-Amc-OH, Fmoc-Trx-OH
- Product code:FAA1647
- CAS No.:167690-53-1
- Formula:C23H25NO4
- Storage temperature:2-8°C
- Molecular weight:379,46 g/mol
- Purity :min. 99%
from €55.00
description
Fmoc-AMCHC is used as a linker in solid-phase peptide synthesis to construct various biologically active conjugates. This fragment is present in many Antibody-Drug Conjugates (Kadcyla®, IMMU-132).
references
Benesova, Martina; Bauder-Wuest, Ulrike; Schaefer, Martin; Klika, Karel D.; Mier, Walter; Haberkorn, Uwe; Kopka, Klaus; Eder, Matthias; J. Med. Chem. 2016; 59(5): 1761-1775. DOI:10.1021/acs.jmedchem.5b01210;
Behrens et al PCT Int. Appl. (2011), WO 2011089255 A1.
Zhu et al PCT Int. Appl. (2019), WO 2019011166 A1.
Do you need further information about this product?
get in contact
We found other products you might like!
