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Fmoc-DfAbu-OH (rac)
Chemical name: (RS)-2-(9-Fluorenylmethyloxycarbonyl)amino-4,4-difluorobutyric acid // Synonyms: (R,S)-Fmoc-2-amino-4,4-difluoro-butyric acid, Fmoc-2-amino-4,4-difluorobutyric acid (rac), Fmoc-2-amino-4,4-difluorobutanoic acid (rac), Fmoc-F2Abu-OH (rac),(RS)-Fmoc-2-amino-4,4-difluoroethylglycin e, Fmoc-DfeGly-OH (rac)
- Product code:FAA3450
- CAS No.:1260640-43-4
- Formula:C19H17F2NO4
- Storage temperature:2-8°C
- Molecular weight:361,34 g/mol
from €200.00
description
Purity > 95% (HPLC)
references
Phe*-Ala-based pentapeptide mimetics are BACE inhibitors: P2 and P3 SAR; J. Lamar, J. Hu, A. B. Bueno, H. C. Yang, D. Guo, J. D. Copp, J. McGee, B. Gitter, D. Timm, P. May, J. McCarthy and S. H. Chen; Bioorg Med Chem Lett 2004; 14: 239-43. https://doi.org/10.1016/j.bmcl.2003.09.084
SAR and pharmacokinetic studies on phenethylamide inhibitors of the hepatitis C virus NS3/NS4A serine protease; S. Malancona, S. Colarusso, J. M. Ontoria, A. Marchetti, M. Poma, I. Stansfield, R. Laufer, A. Di Marco, M. Taliani, M. Verdirame, O. Gonzalez-Paz, V. G. Matassa and F. Narjes; Bioorg Med Chem Lett 2004; 14: 4575-9. https://doi.org/10.1016/j.bmcl.2004.05.093
Novel, potent phenethylamide inhibitors of the hepatitis C virus (HCV) NS3 protease: probing the role of P2 aryloxyprolines with hybrid structures; F. Orvieto, U. Koch, V. G. Matassa and E. Muraglia; Bioorg Med Chem Lett 2003; 13: 2745-8.
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