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Fmoc-L-Lys(Myr)-OH
Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-myristoyl-L-lysine // Synonyms: Fmoc-Lys(Myr)-OH, Fmoc-Lys(myristoyl)-OH, N-alpha-Fmoc-N-epsilon-tetradecanoyl-L-lysine, (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-tetradecanamidohexanoic acid
- Product code:FAA7490
- CAS No.:1128181-23-6
- Formula:C35H50N2O5
- Storage temperature:2-8°C
- Molecular weight:578,78 g/mol
- Purity :min. 99%
- Enantiomeric Purity:min. 99,7%
from €80.00
description
Fmoc-Lys(Myr) is used by Bristol-Myers Squibb in the synthesis of immunomodulating cyclic peptides
references
Gillman, Kevin W.; Goodrich, Jason; Langley, David R.; Scola, Paul Michael PCT Int. Appl. (2018), WO 2018085750 A2; Sirtuin Sirt6 modulating species can be investigated using myristoyl-peptides, that have been synthesized using Fmoc-Lys(Myr), Lin, Hening U.S. (2016), US 9249183 B2; Myristoyl-peptides are used in Sirtuin 1/2/3/6 activity research. Liu, Jiajia; Zheng, Weiping Organic & Biomolecular Chemistry (2016), 14(25), 5928-5935. DOI:10.1039/C5OB02339D; Chiang, Ying-Ling; Lin, Hening Organic & Biomolecular Chemistry (2016), 14(7), 2186-2190. DOI:10.1039/C5OB02609A.
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