Mal-L-Dap(Boc)-OSu

Chemical name: N-alpha-Maleimido-N-beta-Boc-L-2,3-diaminopropionic acid NHS ester // Synonyms: Mal-Dap(Boc)-NHS, Mal-Dpr(Boc)-Osu, Mal-Dpr(Boc)-NHS, (S)-maleoyl-DPR(boc)-OSu, (S)-maleoyl-DPR(boc)-NHS, 2,5-dioxopyrrolidin-1-yl (2S)-3-{[(tert-butoxy)carbonyl]amino}-2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoate, Mal-Dap(Boc)-Osu

  • Product code:MAA1120
  • CAS No.:1703778-79-3
  • Formula:C16H19N3O8
  • Storage temperature:-20°C
  • Molecular weight:381,34 g/mol
  • Purity :min.98%
  • Enantiomeric Purity:min.99,7%

from €96.00

Grouped product items
Qty Packing unit Price SKU Availability
100 mg
€96.00
MAA1120.0100
<10 Business days
250 mg
€160.00
MAA1120.0250
<10 Business days
500 mg
€288.00
MAA1120.0500
<10 Business days
1 g
€448.00
MAA1120.1000
<10 Business days
5 g
€1,600.00
MAA1120.5000
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description

Mal-Dap(Boc)-OSu is used in drug conjugate construction leading to more stable conjugates due to Dap neighbouring-group assistance. This strategy is widely used by Seagen Inc. and others.

references

PCT Int. Appl. (2015), WO 2015057699 A2

PCT Int. Appl. (2017), WO 2017196598 A1

PCT Int. Appl. (2020), WO2020132655 A1

PCT Int. Appl. (2021), WO2021207701 A1

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