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Fmoc-L-Thr(tBu)-L-Thr[PSI(Me,Me)Pro]-OH
Chemical name: (4S,5R)-3-(N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-t-butyl-L-threonine)-2,2,5-trimethyloxazolidine-4-carboxylic acid // Synonyms: Fmoc-Thr(tBu)-Thr[PSI(Me,Me)Pro]-OH
- Product code:PSI1420
- CAS No.:1676104-73-6
- Formula:C30H38N2O7
- Storage temperature:2-8°C
- Molecular weight:538,63 g/mol
from €95.00
description
Pseudoprolines derived from Serine and Threonine have developed to standard building blocks for peptide synthesis since their invention.
references
Pseudo-Prolines as a Molecular Hinge: Reversible Induction of cis Amide Bonds into Peptide Backbones; P. Dumy, M. Keller, D. E. Ryan, B. Rohwedder, T. Wöhr and M. Mutter; J. Am. Chem. Soc. 1997; 119: 918-925. https://doi.org/10.1021/ja962780
Pseudo-Prolines as a Solubilizing, Structure-Disrupting Protection Technique in Peptide Synthesis; T. Wöhr, F. Wahl, A. Nefzi, B. Rohwedder, T. Sato, X. Sun and M. Mutter; J. Am. Chem. Soc. 1996; 118: 9218-9227. https://doi.org/10.1021/ja961509q
Expediting the Fmoc solid phase synthesis of long peptides through the application of dimethyloxazolidine dipeptides; P. White, J. W. Keyte, K. Bailey and G. Bloomberg; J. Pept. Sci. 2004; 10: 18-26. https://doi.org/10.1002/psc.484
Pseudoprolines as Removable Turn Inducers: Tools for the Cyclization of Small Peptides; D. Skropeta, K. A. Jolliffe, and P. Turner; J. Org. Chem. 2004; 69: 8804-8809. https://doi.org/10.1021/jo0484732
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