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Z-L-Arg-L-Arg-AMC*2HCl
Chemischer Name: N-alpha-benzyloxycarbonyl-L-arginyl-L-arginine-7-amido-4-methylcoumarin-dihydrochloride // Synonyme: Z-RR-AMC, Z-Arg-Arg-AMC, Z-Arg-Arg-AMC hydrochloride salt, Z-Arg-Arg-MCA, N-alpha-Cbz-Arg-Arg 7-Amido-4-methylcoumarin hydrochloride; Component: CAS 88937-61-5
- Art-Nr.:ZAA1470
- CAS Nr.:140686-23-3
- Formel:C30H39N9O6*2HCl
- Lagertemperatur:2-8°C
- Molare Masse:621,69*72,91 g/mol
Ab 215,00 €
description
Fluorogenic Cathepsin B and other cysteine protease substrate.
references
Purified NS2B/NS3 Serine Protease of Dengue Virus Type 2 Exhibits Cofactor NS2B Dependence for Cleavage of Substrates with Dibasic Amino Acids in Vitro. R. Yusof, S. Clum, M. Wetzel, H. M. Krishna Murthy, and R. Padmanabhan; J. Biol. Chem. 2000; 275, 9963-9969. https://doi.org/10.1074/jbc.275.14.9963
Function-based isolation of novel enzymes from a large library. M. J. Olsen, D.Stephens, D. Griffiths, P. Daugherty, G. Georgiou, B. L. Iverson; Nat. Biotechnol. 2000; 18, 1071-1074. https://doi.org/10.1038/80267
Catalytic Mechanism of Cruzain from Trypanosoma cruzi as determined from solvent kinetic isotope effects of steady-state and pre-steady-state kinetics. X. Zhai, T. D. Meek; Biochemistry 2018; 57, 3176-3190. https://doi.org/10.1021/acs.biochem.7b01250
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