Azide-PEG(4)-SNAP

Chemischer Name: N-(4-(((2-amino-9H-purin-6-yl)oxy)methyl)benzyl)-1-azido-3,5,7,9-tetraoxadodecan-12-amide // Synonyme: Azide-PEG-SNAP, Azide-PEG-Benzylguanine, Azide-PEG-BG, Azide-PEG(4)-Benzylguanine, Azide-PEG(4)-BG

  • Art-Nr.:RL-3960
  • Formel:C24H33N9O6
  • Lagertemperatur:-20°C
  • Molare Masse:543,59 g/mol

Ab 300,00 €

Gruppiert Produkte - Artikel
Anzahl Verpackungsgröße Preis SKU Warenverfügbarkeit
5 mg
300,00 €
RL-3960.0005
<10 Arbeitstage
25 mg
1.200,00 €
RL-3960.0025
<10 Arbeitstage
Sicherheitsdatenblätter
description

Azide conjugated benzylguanine (BG). The BG moiety reacts specifically and rapidly with the so-called SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional azide functionality suitable for further conjugation via Click Chemistry.

The additional PEG moiety increases overall solubility.


references

Yeast Three-Hybrid Screening for Identifying Anti-Tuberculosis Drug Targets; S. Moser, K. Johnsson; ChemBioChem 2013; 14(17): 2239-2242. https://doi.org/10.1002/cbic.201300472

A yeast-based screen reveals that sulfasalazine inhibits tetrahydrobiopterin biosynthesis; C. Chidley, H. Haruki, M. Grønlund Pedersen. E. Muller, K. Johnsson; Nat. Chem. Biol. 2011; 7: 373-383. https://doi.org/10.1038/nchembio.557

Caged Substrates for Protein Labeling and Immobilization; S. Banala, A. Arnold, K. Johnsson; ChemBioChem 2008; 9(1): 38-41. https://doi.org/10.1002/cbic.200700472


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