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Blog - Page 4
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HMPO: A pH-Responsive Linker for Targeted Drug Delivery
HMPO (5-(hydroxymethyl)pyrogallol orthoester), a plasma-stable, pH-sensitive, 1,6-self-immolative crosslinker derived from the natural product gallic acid. Discover its properties!
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PotM: MYTsA – A Novel Ynamide Coupling Reagent
Discover MYTsA as coupling reagent for peptide synthesis in “traditional” C→N and vice versa in “natural” N→C direction. Avoid racemization and benefit of improved atom economy!
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Workshop: The Chemistry behind how life startet on Earth
You missed our Workshop with Prof. Thomas Carell? As unpublished data was shown, the recording of the workshop will just be available on our homepage in a few weeks. If you would like to be informed please get in contact via info@iris-biotech.de.
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Hidden Champion – The Tetrahydropyranyl Protective Group
Tetrahydropyranyl (THP) is an excellent protective group for hydroxy and thiol moieties but rarely used in solid-phase peptide synthesis (SPPS). Discover its advantages, e.g., over O/StBu and Trt.
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Common Side Reactions in Fmoc Solid-Phase Peptide Synthesis
Collect information about the most common side reactions during Fmoc SPPS and how to avoid them! Choose your building blocks and conditions wisely to avoid unnecessary trouble!
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GGFG Motif for ADC Construction
To address both chemical and IP considerations in self-immolating linker applications, we propose shifting from the commonly used Val-Cit-PAB linker to the less explored Gly-Gly-Phe-Gly-formyl motif.
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PotM: Versatile TentaGel® Resins
Discover the diversity of TentaGel® Resins! Read our blog to get more information about our latest product additions and possible applications and find the right resin for your research endeavors!
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