Blog - Life Sciences

  1. UAA! Discover Aminocoumarinyl Lysine

    We say "UAA"! By genetic code expansion you can incorporate our novel aminocoumarinyl lysine in your favorite protein where it serves you as fluorescent probe or photo-activatable caged lysine.

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  2. New Maillard Products for Peptide Synthesis and Analytics

    Benefit of our latest Maillard Reaction Product additions! Use them as reference standard for quality control and food analysis or synthesize modified peptides for research studies.

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  3. A Fluorescent Probe for “Hard and Soft” Reactive Metabolites

    Discover CysGluDan, a new fluorescent probe for the detection of reactive metabolites in drug development, which can detect both "soft" and "hard" nucleophiles. 

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  4. Carboxymethyl Amino Acid Derivatives

    Level up! Carboxymethyl-modified amino acid building blocks suitable for incorporation by solid-phase peptide synthesis. Learn more about available derivatives and their properties.

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  5. 2-Cyanopyridines for Click-Like Reactions

    Have an additional ace up your sleeve for selective and efficient peptide modification, cyclization, and/or bioconjugation. Explore 2-cyanopyridines for click-like reactions. Get more information!

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  6. Aminothiols for Versatile Side-Chain Modification

    Beyond cysteines: Unlock targeted side-chain modifications of your peptides and proteins via the introduction of 1,2-aminothiols and subsequent click-like functionalization. 

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  7. Azobenzene Photoswitches

    Engineer shape-shifting peptides, controllable by a laser as magic wand! In this newsletter, we’ll explore the possibilities of photo switchable building blocks based on azobenzene.

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  8. PotM: Oligomeric Sarcosine Building Blocks

    You are looking for monodisperse Sarcosines? You want to use Sarcosine for SPPS? You need to improve your drug's hydrophilicity and search for PEG alternatives? Read on!

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  9. A Tetrazole-Substituted Lysine as PTM Isostere

    The tetrazole isostere of malonyllysine is thermally stable and does not suffer from decarboxylation. Discover our building blocks suitable for incorporation via solid-phase peptide synthesis.

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  10. Cyanobenzothiazole (CBT) Derivatives for “Click” Conjugation

    Discover the cyanobenzothiazole (CBT) click reaction, a not (yet) so well-known biocompatible and bio-orthogonal mechanism faster than the famous azide-alkyne cycloaddition (CuAAC).

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