Linkerology

09/08/2023

Conjugating Natural Products (3)

The potential of natural products of daily life, such as 6-shogaol from ginger (Zingiber officinale), can flourish if the active ingredient is conjugated to an appropriate carrier via Linkerology®.

News Linkerology

25/07/2023

Functionalization of Carbon Materials by Linker Attachment

Allotropes of carbon show distinct characteristics in structure and e.g. electric and biophysiological properties. Discover how these materials can be further exploited by linker attachment!

Functionalization of Carbon Materials by Linker Attachment

News Linkerology

27/06/2023

Functionalization of (Inert) Polymeric Surfaces

Plasma technology allows to equip inert polymers such as poly(ethylene) or polystyrene with functional groups like amine or carboxylate enabling further conjugations and applications. Read on!

Functionalization of (Inert) Polymeric Surfaces

News Linkerology

30/05/2023

Conjugating Natural Products (2)

Infinite like the deep sea – marine natural products are an infinite source of (bio)active compounds. In this series we present how natural products can be conjugated to empower their inherent potential.

News Linkerology

18/04/2023

Conjugating Natural Products (1)

From evolution to solution - natural products are an infinite source of (bio)active compounds. In this series we present how natural products can be conjugated to empower their inherent potential.

News Linkerology Building Blocks Product Focus

21/03/2023

Maleimide Crosslinkers

Maleimides provide versatile options for connecting payloads to proteins and other biomolecules. Discover how our bifunctional thiol reactive crosslinkers can support your project. Read on!

News Product of the month Linkerology Building Blocks Life Sciences Click Chemistry

21/03/2023

PotM: Perfluorobiphenyl Building Blocks for Site-Selective Cysteine Conjugation

Herein, we present functionalized perfluorobiphenyl building blocks which can be used for site-selective π-clamp mediated cysteine conjugation. Read on for more details about this general method!

PotM: Perfluorobiphenyl Building Blocks for Site-Selective Cysteine Conjugation

News Linkerology Life Sciences Product Focus

07/02/2023

Choose your Taste – Functionalized Halo/Snap/Clip Substrates

The HaloTag®, SNAP-Tag® and CLIP-Tag^TM represent versatile tools for the specific, covalent attachment of in principle any molecule of choice to a protein of interest. Discover our substrates!

Choose your Taste – Functionalized Halo/Snap/Clip Substrates

News Linkerology Product Focus

07/02/2023

Temporary Activity Masking via Self-Immolative Linkage

(Bi)functional dioxoborolane and disulfide-based self-immolative linkers – mode of action and application examples for the detection of H₂O₂, for prodrug design, and reversible peptide cyclization.

Temporary Activity Masking via Self-Immolative Linkage

News Linkerology Drug Delivery Product Focus Custom Synthesis

28/10/2022

Linker Technologies for Sophisticated Bioconjugations

Linkers serve as versatile tools, e.g. during SPPS or for the sophisticated (self-immolative) conjugation of a potent small molecule to a carrier. Check out our selection of over 100 readily available linkers.