Fmoc-Sieber-PS resin

Nombre químico: Fmoc-Sieber-polystyrene resin // Sinónimos: 9-(9-Fluorenylmethyloxycarbonylamino)-9H-xanthen-3-yl-oxymethylpolystyrene

  • Nº Artículo:BR-2000
  • Nº CAS:915706-90-0
  • Storage temperature:2-8°C
  • Tamaño de partícula:100-200 mesh
  • DVB reticulación:1% DVB
  • Cargando:0.5-0.9 mmol/g

from 170,00 €

Grouped product items
Cantidad Unidad de venta Precio Unidad de almacenamiento de stock (SKU) Disponibilidad
1 g
170,00 €
BR-2000.0001
<10 días laborables
5 g
290,00 €
BR-2000.0005
<10 días laborables
25 g
1.150,00 €
BR-2000.0025
<10 días laborables
50 g
2.300,00 €
BR-2000.0050
<10 días laborables
100 g
3.720,00 €
BR-2000.0100
<10 días laborables
Hoja de seguridad
description

Fmoc-Sieber amide resin is an acid-labile carrier for solid phase synthesis of peptide amides. Cleavage can be achieved with only 1% TFA in DCM making them an ideal carrier for the synthesis of protected peptide fragments in fragment condensation strategies for the synthesis of long peptides. It has also been used in organic synthesis of acid-sensitive compounds, for targeted synthesis of primary amines and N-alkylated secondary carboxyamides.


references

Template-directed approach to solid-phase combinatorial synthesis of furan-based libraries; P. Gupta, S. K. Singh, A. Pathak and B. Kundu; Tetrahedron 2002; 58: 10469-10474. https://doi.org/10.1016/s0040-4020(02)01396-0

Multiple solid phase synthesis of (RS)-1-aminophosphinic acids; E. A. Boyd, W. C. Chan and V. M. Loh; Tetrahedron Letters 1996; 37: 1647-1650. https://doi.org/10.1016/0040-4039(96)00082-2

Reductive alkylation of 9-amino-xanthen-3-yloxymethylpoly(styrene): a novel procedure for the synthesis of peptidyl N-alkyl amides by Fmoc/But chemistry; W. C. Chan and S. L. Mellor; Journal of the Chemical Society, Chemical Communications 1995: 1475-1477. https://doi.org/10.1039/c39950001475

Facile synthesis of protected C-terminal peptide segments by Fmoc/But solid-phase procedures on N-Fmoc-9-amino-xanthen-3-yloxymethyl polystyrene resin; W. C. Chan, P. D. White, J. Beythien and R. Steinauer; Journal of the Chemical Society, Chemical Communications 1995: 589-592. https://doi.org/10.1039/c39950000589

A new acid-labile anchor group for the solid-phase synthesis of C-terminal peptide amides by the Fmoc method; P. Sieber; Tetrahedron Letters 1987; 28: 2107-2110. https://doi.org/10.1016/s0040-4039(00)96055-6



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