Fmoc-L-Thz(Me2)-OH

Nombre químico: (R)-N-(9-Fluorenylmethyloxycarbonyl)-2,2-dimethyl-thiazolidine-4-carboxylic acid // Sinónimos: Fmoc-Thz(Me2)-OH, Fmoc-Cys(PsiMe,MePro)-OH, Fmoc-Cys(PsiMe,MePro), Fmoc-Cysteine Pseudoproline

  • Nº Artículo:FAA1437
  • Nº CAS:873842-06-9
  • Fórmula:C21H21NO4S
  • Storage temperature:2-8°C
  • Masa molecular:383,46 g/mol
  • Pureza:min. 99%
  • Pureza Enantiomérica:min. 99,7%

from 125,00 €

Grouped product items
Cantidad Unidad de venta Precio Unidad de almacenamiento de stock (SKU) Disponibilidad
5 g
125,00 €
FAA1437.0005
<10 días laborables
25 g
500,00 €
FAA1437.0025
<10 días laborables
100 g
1.500,00 €
FAA1437.0100
peticón
Hoja de seguridad
description

A cysteine pseudoproline with short deprotection times in TFA.  Deprotected procedure: Dry resin (5 mg) was treated with TFA/TIS/H2O (95:2.5:2.5) for several hours at rt. The cleavage mixture was evaporated with a stream of argon, precipitated with Et2O, centrifuged and the pellet was redissolved in H2O/CH3CN (1:1) for analysis by HPLC and LCMS. The deprotection time and temperature is sequence-dependent.



references

Cysteine Pseudoprolines for Thiol Protection and Peptide Macrocyclization Enhancement in Fmoc-Based Solid-Phase Peptide Synthesis. Tobias M. Postma, Fernando Albericio; Org. Lett. 2014; 16(6): 1772-1775. DOI: 10.1021/ol5004725


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