Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
EUR
Contacto rápido
Por favor envíeme más información sobre
Fmoc-L-trans-Hyp(Nfb)-OH
Nombre químico: N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-(nonafluoro-t-butyl)-trans-L-hydroxyproline // Sinónimos: Fmoc-Hyp(nonafluoro-t-butyl)-OH (trans), (2S,4R)-1-(((9H-fluoren-9-yl)methoxy)carbonyl)-4-(1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-yloxy)pyrrolidine-2-carboxylic acidFmoc-L-Hyp(Nfb)-OH (t rans), Fmoc-L-Hyp(Nfb)-OH (2S,4R), Fmoc-trans-Hyp(
- Nº Artículo:FAA4560
- Nº CAS:1622172-75-1
- Fórmula:C24H18F9NO5
- Storage temperature:2-8°C
- Masa molecular:571,39 g/mol
from 900,00 €
description
The nonafluoro-t-butyl group (Nfb) equips the proline moiety with both polarity and hydrophobicity. It is stable to standard SPPS cleavage conditions for Wang typical linkers, like 90% TFA/10% scavengers.
references
(2S,4R)- and (2S,4S)-Perfluoro-tert-butyl 4-Hydroxyproline: Two Conformationally Distinct Proline Amino Acids for Sensitive Application in 19F NMR; Caitlin M. Tressler and Neal J. Zondlo; J. Org. Chem. 2014; 79: 5880−5886; DOI: org/10.1021/jo5008674
ã-(S)-Trifluoromethyl proline: evaluation as a structural substitute of proline for solid state 19F-NMR peptide studies; Vladimir Kubyshkin, Sergii Afonin, Sezgin Kara, Nediljko Budisa, Pavel K. Mykhailiuk, Anne S. Ulrich; Org. Biomol. Chem. 2015; 13: 3171-3181; DOI: 10.1039/c5ob00034c.
* Disclaimer
We refer to our general terms and conditions.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
¿Necesita más información sobre este producto?
ponerse en contacto
Folletos y volantes
¡Otros productos que también podrían interesarle!
