Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
EUR
Contacto rápido
Por favor envíeme más información sobre
Biotin-aniline
Nombre químico: N-(4-aminophenethyl)-biotinamide // Sinónimos: Btn-An, Biot-aniline, N-[2-(4-aminophenyl)ethyl]hexahydro-2-oxo-(3aS,4S,6aR)-1H-thieno[3,4-d]imidazole-4-pentanamide,N-(4-aminophenethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl )pentanamide, 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-t
- Nº Artículo:LS-3970
- Nº CAS:769933-15-5
- Fórmula:C18H26N4O2S
- Storage temperature:-20°C
- Masa molecular:362,49 g/mol
- Pureza:min. 98%
from 170,00 €
description
Biotin-aniline labelling with APEX2 can capture all 13 mitochondrial messenger RNAs while leaving all cyrtoplasmic RNAs untouched. APEX2-mediated Btn-An labeling of RNA is thus a promising method for mapping the subcellular transcriptome, which could shed light on their functions in cell physiology. Hence it provides an alternative methodology to the common Biotin-phenol labelling.
references
Expanding APEX2 Substrates for Spatial-specific Labeling of Nucleic Acids and Proteins in Living Cells; Y. Zhou, G. Wang, P. Wang, Z. Li, T. Yue, J. Wang, P. Zou; Angew. Chem. Int. Ed. 2019; 58(34): 1763-11767. https://doi.org/10.1002/anie.201905949.
Spatiotemporal profiling of cytosolic signaling complexes in living cells by selective proximity proteomics; M. Ke, X. Yuan, A. He, P. Yu, W. Chen, Y. Shi, T. Hunter, P. Zou, R. Tian; Nat. Commun. 2021; 12: 71. https://doi.org/10.1038/s41467-020-20367-x.
Mapping spatial transcriptome with light-activated proximity-dependent RNA labeling; P. Wang, W. Tang, Z. Li, Z. Zou, Y. Zhou, R. Li, T. Xion, J. Wang, P. Zou; Nat. Chem. Biol. 2019; 15(11): 1110-1119. https://doi.org/10.1038/s41589-019-0368-5.
Fabrication and characterization of heparin functionalized membrane-mimetic assemblies; P.-Y. Tseng, S. M. Rele, X.-L. Sun, E. L. Chaikof; Biomaterials 2006; 27(12): 2627-2636. https://doi.org/10.1016/j.biomaterials.2005.10.032.
Quantification of streptavidin adsorption in microtitration wells; L. Välimaa, K. Pettersson, J. Rosenberg, M. Karp, T. Lövgren; Anal. Biochem. 2004; 331(2): 376-384. https://doi.org/10.1016/j.ab.2004.04.003.
* Disclaimer
We refer to our general terms and conditions.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
¿Necesita más información sobre este producto?
ponerse en contacto
Folletos y volantes
¡Otros productos que también podrían interesarle!
