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Mal-AMCHC-N-Propargylamide
Nombre químico: trans-4-[(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]-N-(prop-2-yn-1-yl)cyclohexane-1-carboxamide // Sinónimos: MCC-Yne, SMCC Propargyl amide, Maleimido-AMCHC-Propargylamide, Mal-AMCHC-N-Propynyl
- Nº Artículo:MAA1100
- Nº CAS:2027476-42-0
- Fórmula:C15H18N2O3
- Storage temperature:2-8°C
- Masa molecular:274,32 g/mol
- Pureza:min. 98%
from 120,00 €
description
Related CAS number: 1036847-90-1 of the (cis,trans) stereoisomer mixture.
Used as a bio-conjugation reagent for antibody-drug-conjugate synthesis using Click-Chemistry.
references
Antibody Conjugates of 7-Ethyl-10-hydroxycamptothecin (SN-38) for Targeted Cancer Chemotherapy. Sung-Ju Moon, Serengulam V. Govindan, Thomas M. Cardillo, Christopher A. D’Souza, Hans J. Hansen, David M. Goldenberg; J. Med. Chem. 2008; 51(21): 6916-6926. DOI: 10.1021/jm800719t
WO2019154120A1
US20160303253A1
US20170360770A1
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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