Biotin-AEEA-OPhOMe

Nombre químico: 2-(2-(2-(Biotinamido)ethoxy)ethoxy)acetic acid 4-methoxyphenyl ester // Sinónimos: 4-methoxyphenyl 2-(2-(2-(Biotinamido)ethoxy)ethoxy)acetate, 4-methoxyphenyl 2-(2-(2-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethoxy)ethoxy)acetate

  • Nº Artículo:RL-3100
  • Nº CAS:2546513-67-9
  • Fórmula:C23H33N3O7S
  • Storage temperature:-20°C
  • Masa molecular:495,59 g/mol
  • Pureza:min. 95%

from 585,00 €

Grouped product items
Cantidad Unidad de venta Precio Unidad de almacenamiento de stock (SKU) Disponibilidad
250 mg
585,00 €
RL-3100.0250
<10 días laborables
1 g
1.750,00 €
RL-3100.0001
<10 días laborables
description

Methodology for highly selective N-terminal chemical acylation of expressed proteins. This 4-methoxyphenyl ester adds selectively to Gly-His-tags of proteins, while it does not react with epsilon amino functions of surface accessible lysines. Therefore, it expresses a unique possibility to label proteins regiospecific at the Gly-His tag position, enabling a wide application field in chemical biology and for biopharmaceuticals.


references

Selective N-terminal acylation of peptides and proteins with a Gly-His tag sequence; Manuel C. Martos-Maldonado, Christian T. Hjuler, Kasper K. Sørensen, Mikkel B. Thygesen, Jakob E. Rasmussen, Klaus Villadsen, Søren R. Midtgaard, Stefan Kol, Sanne Schoffelen, and Knud J. Jensen; Nature Communications 2018; 9: 3307. DOI: 10.1038/s41467-018-05695-3

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