Name: Alkyne-PEG(5)-SNAP
SKU: RL-3940
Availability: InStock

Grouped product items

Cantidad

Unidad de venta

Precio

Unidad de almacenamiento de stock (SKU)

5 mg

300,00 €

RL-3940.0005

25 mg

1.200,00 €

RL-3940.0025

description

Alkyne conjugated benzylguanine (BG). The BG moiety reacts specifically and rapidly with the so-called SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation.

The additional PEG moiety increases overall solubility.

references

Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand; J. Broichhagen, A. Damijonaitis, J. Levitz, K. R. Sokol, P. Leippe, D. Konrad, E. Y. Isacoff, D. Trauner; ACS Cent Sci. 2015; 1(7): 383-93. https://doi.org/10.1021/acscentsci.5b00260

A Semisynthetic Fluorescent Sensor Protein for Glutamate; M. A. Brun, K.-T. Tan, R. Griss, A. Kielkowska, L. Reymond, K. Johnsson; J. Am. Chem. Soc. 2012; 134(18): 7676-7678. https://doi.org/10.1021/ja3002277

Fura-2FF-based calciumindicator for proteinlabeling; A. A. Ruggiu, M. Bannwarth, K. Johnsson; Org. Biomol. Chem. 2010; 8: 3398-3401. https://doi.org/10.1039/C000158A

Indo-1 Derivatives for Local Calcium Sensing; M. Bannwarth, I. R. Corrêa Jr., M. Sztretye, S. Pouvreau, C. Fellay, A. Aebischer, L. Royer, E. Ríos, K. Johnsson; ACS Chem. Biol. 2009; 4(3): 179-190. https://doi.org/10.1021/cb800258g

Caged Substrates for Protein Labeling and Immobilization; S. Banala, A. Arnold, K. Johnsson; ChemBioChem 2008; 9(1): 38-41. https://doi.org/10.1002/cbic.200700472