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DBCO-Suc-SS-COOH
Sinónimos: DBCO-SS-COOH
- Nº Artículo:RL-4110
- Nº CAS:2749426-25-1
- Fórmula:C24H24N2O4S2
- Storage temperature:2-8°C
- Masa molecular:468,59 g/mol
from 450,00 €
description
Disulfide-Based Linker bearing a clickable DBCO moiety and a carboxylic acid as functional group for crosslinking. The disulfide bond can be cleaved by reduction.
references
Linker Technologies for Antibody-Drug Conjugates; B. Nolting; Antibody-Drug Conjugates L. Ducry 2013; 1045: 71-100. https://doi.org/10.1007/978-1-62703-541-5_5
Current ADC linker chemistry; N. Jain, S. W. Smith, S. Ghone, B. Tomczuk; Pharm. Res. 2015; 32: 3526-3540. https://doi.org/10.1007/s11095-015-1657-7
Antibody drug conjugates: design and selection of linker, payload and conjugation chemistry; J. R. McCombs, S. C. Owen; AAPS J. 2015; 17(2): 339-351. https://doi.org/10.1208/s12248-014-9710-8
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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