Fmoc-Val-Cit-PAB

Nom chimique: 9-Fluorenylmethyloxycarbonyl-valyl-citrullyl-4-aminobenzylalcohol // Synonymes: 9-Fluorenylmethyloxycarbonyl-valyl-citrullyl-4-aminobenzylalcohol (9H-fluoren-9-yl)methyl(S)-1-((S)-1-(4-(hydroxymethyl)phenylamino)-1-oxo-5-ureidopentan-2-ylamino)-3-methyl-1-oxobutan-2-ylcarbamate

  • n° Art.:ADC1030
  • n° CAS:159858-22-7
  • Formule:C33H39N5O6
  • Storage temperature:-20°C
  • Masse moléculaire:601,29 g/mol
  • Pureté:min. 97%

from 190,00 €

Grouped product items
Nombre Unité de vente Prix SKU Disponibilité
250 mg
190,00 €
ADC1030.0250
<10 jour ouvrables
1 g
550,00 €
ADC1030.1000
<10 jour ouvrables
5 g
2 200,00 €
ADC1030.5000
<10 jour ouvrables
Fiches de données de sécurité
description

Linker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell.

references

Laurent Ducry (ed.), Antibody-Drug Conjugates, Methods in Molecular Biology, vol. 1045, DOI 10.1007/978-1-62703-541-5_5, # Springer Science+Business Media, LLC 2013.

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