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Fmoc-L-Phe(4-NH-Poc)-OH
Nom chimique: N-alpha-(9-Fluorenylmethyloxycarbonyl)-4-propargyloxycarbonylamino-L-phenylalanine // Synonymes: Fmoc-Phe(4-NH-Poc)-OH, Fmoc-L-Aph(Poc)-OH, Fmoc-4Aph(Poc), Fmoc-L-4Aph(Poc)-OH, Fmoc-L-4-Aph(Poc)-OH, Fmoc-p-amino-Phe(Poc)-OH, Fmoc-L-Phe(4-NH-Poc)-OH, Fmoc-4Aph(Pryoc),Fmoc-L-4Aph(Pryoc)-OH, Fmoc- L-4-Aph(Pryoc)-OH, Fmoc-p-amino-Phe(Pryoc)-OH
- n° Art.:FAA7720
- n° CAS:2576508-07-9
- Formule:C28H24N2O6
- Storage temperature:2-8°C
- Masse moléculaire:484,5 g/mol
- Pureté:min. 98%
- Pureté Énantiomérique:min. 99,7%
from 108,00 €
description
Used as an orthogonally protected building block in solid-phase peptide synthesis. Poc-group can be further modified using Click-chemistry.
references
Bioorthogonal Catalysis: A General Method To Evaluate Metal-Catalyzed Reactions in Real Time in Living Systems Using a Cellular Luciferase Reporter System; H. T. Hsu, B. M. Trantow, R. M. Waymouth and P. A. Wender; Bioconjug Chem 2016; 27: 376-82. https://doi.org/10.1021/acs.bioconjchem.5b00469
N-alkynyl derivatives of 5-fluorouracil: susceptibility to palladium-mediated dealkylation and toxigenicity in cancer cell culture; J. T. Weiss, C. Fraser, B. Rubio-Ruiz, S. H. Myers, R. Crispin, J. C. Dawson, V. G. Brunton, E. E. Patton, N. O. Carragher and A. Unciti-Broceta; Front Chem 2014; 2: 56. https://doi.org/10.3389/fchem.2014.00056
Palladium-triggered deprotection chemistry for protein activation in living cells; J. Li, J. Yu, J. Zhao, J. Wang, S. Zheng, S. Lin, L. Chen, M. Yang, S. Jia, X. Zhang and P. R. Chen; Nat Chem 2014; 6: 352-61. https://doi.org/10.1038/nchem.1887
Propargyloxycarbonyl and propargyl groups for novel protection of amino, hydroxy, and carboxy functions; Y. Fukase, K. Fukase and S. Kusumoto; Tetrahedron Letters 1999; 40: 1169-1170. https://doi.org/10.1016/s0040-4039(98)02555-6
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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