Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
EUR
Contact rapide
Veuillez m'envoyer plus d'informations sur
Fmoc-Ac7c-OH
Nom chimique: 1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cycloheptane-1-carboxylic acid
- n° Art.:FAA8670
- n° CAS:188751-56-6
- Formule:C23H25NO4
- Storage temperature:2-8°C
- Masse moléculaire:379,46 g/mol
from 1 200,00 €
description
This derivative can be used as constrained building block for structure activity relationship studies. Such alpha,alpha-disubstituted amino acids are widely used in peptide design because of their structure promoting effects. The presence of Ac7c allows to adopt beta-turn conformations and to stabilize helical folds.
references
A combined extended and helical backbone for Boc-(Ala-Leu-Ac7c-)2-OMe; I. L. Karle, S. Prasad, P. Balaram; J. Pept. Res. 2004; 63(2): 175-180. https://doi.org/10.1111/j.1399-3011.2003.00120.x.
Direct preparation of diacetals from 1,2-diketones and their use as 1,2-diol protecting groups; A. Hence, S. V. Ley, H. M. I. Osborn, D. R. Owen, J.-F. Poisson, S. L. Warriner, K. E. Wesson; J. Chem. Soc., Perkin Trans. 1, 1997; 2023-2031. https://doi.org/10.1039/A702497E.
Stereochemistry of peptides containing 1-aminocycloheptane-1-carboxylic acid (Ac7c); G. Valle, M. Crisma, C. Toniolo, Sudhanand, R. Balaji Rao, M. Sukumar, P. Balaram, Int. J. Pept. Protein Res. 1991, 38(6): 511-518. https://doi.org/10.1111/j.1399-3011.1991.tb01534.x.
* Disclaimer
We refer to our general terms and conditions.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
Besoin d'informations supplémentaires sur ce produit?
entrer en contact
Des produits qui pourraient également vous intéresser!
