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Fmoc-L-3-(2-cyano-4-pyridyl)-alanine
Nom chimique: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-cyanopyridin-4-yl)propanoic acid // Synonymes: (S)-Fmoc-2-amino-3-(2-cyanopyridin-4-yl)propanoic acid
- n° Art.:FAA9370
- n° CAS:2245755-79-5
- Formule:C24H19N3O4
- Storage temperature:-20°C
- Masse moléculaire:413,43 g/mol
from 400,00 €
references
Synthesis of DNA-Encoded Macrocyclic Peptides via Nitrile-Aminothiol Click Reaction; L. Fan, Y. Yu, C. Jayne, J. R: frost, J. D. Scott; Org. Lett 2023; 25(44): 8038-8042. https://doi.org/10.1021/acs.orglett.3c03284
Enabling Genetic Code Expansion and Peptide Macrocyclization in mRNA Display via a Promiscuous Orthogonal Aminoacyl-tRNA Synthetase; S. E. Iskandar, J. M. Pelton, E. T. Wick, D. L. Bolhuis, A. S. Baldwin, M. J. Emanuele, N. G. Brown, A. A. Bowers; J. Am. Chem. Soc. 2023; 145(3): 1512-1517. https://doi.org/10.1021/jacs.2c11294
Selective thiazoline peptide cyclisation compatible with mRNA display and efficient synthesis; M. Liu, R. Morewood, R. Yoshisada, M. N. Pascha, A. J. P. Hopstaken, E. Tarcoveanu, D. A. Poole, C. A. M. de Haan, C. Nitsche, S. A. K. Jongkees; Chem. Sci. 2023; 14(38): 10561-10569. https://doi.org/10.1039/D3SC03117A
Genetic Encoding of Cyanopyridylalanine for In-Cell Protein Macrocyclization by the Nitrile-Aminothiol Click Reaction; E. H. Abdelkader, H. Qianzhu, J. George, R. Frkic, C. J. Jackson, C. Nitsche, G. Otting, T. Huber; Angew. Chem. Int. Ed. 2022; 61(13): e202114154. https://doi.org/10.1002/anie.202114154
Challenges of short substrate analogues as SARS-CoV-2 main protease inhibitors; S. Ullrich, V. M. sasi, M. C. Mahawaththa, K. B. Ekanayake, R. Morewood, J. George, L. Shuttleworth, X. Zhang, C. Withefield, G. Otting, C. Jackson, C. Nitsche; Bioorg. Med. Chem. Lett. 2021; 50: 128333. https://doi.org/10.1016/j.bmcl.2021.128333
Biocompatible Macrocyclization between Cysteine and 2‑Cyanopyridine Generates Stable Peptide Inhibitors; C. Nitsche, H. Onagi, J.-P. Quek, G. Otting, D. Luo, T. Huber; Org. Lett. 2019; 21(22): 4709-4712. https://doi.org/10.1021/acs.orglett.9b01545
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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