Name: Photo-Stearic acid
SKU: RL-3750
Availability: InStock

Grouped product items

Nombre

Unité de vente

Prix

SKU

Disponibilité

100 mg

1 000,00 €

RL-3750.0100

Fiches de données de sécurité

description

Bifunctional, long and fatty acid like cross-linker suitable for the conjugation of nucleophiles, like amines, with azides or any other functional groups for click chemistry. This linker bears an diazirin ring, which will dismiss N2 under illumination with UV light. The remaining carbene will undergo spontaneous insertion and addition reaction with any neighboring molecule and irreversibly form a covalent bond. Photoaffinity labeling has been used as powerful tool for the identification of ligand-protein and protein-protein interactions.

Protect from sunlight.

references

Preparation of Short Oligonucleotides via the Phosphoramidite Method Using a Tetrazole Promoter in a Catalytic Manner; Y. Hayakawa, M. Kataoka; J. Am. Chem. Soc. 1997; 119(49): 11758-11762. https://doi.org/10.1021/ja970685b.

Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles; C. Thiele, M. J. Hannah, F. Fahrenholz, W. B. Huttner; Nat. Cell Biol. 2000; 2(1): 42-49. https://doi.org/10.1038/71366.

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