PFB-mercaptopropionyl-PEG3-N3

Nom chimique: Perfluorobiphenyl-mercaptopropionyl-PEG(3)-N3 // Synonymes: N-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)-3-((perfluoro-[1,1'-biphenyl]-4-yl)thio)propanamide

  • n° Art.:RL-4030
  • Formule:C23H21F9N4O4S
  • Storage temperature:-20°C
  • Masse moléculaire:620,49 g/mol
  • Pureté:min.98%

from 300,00 €

Grouped product items
Nombre Unité de vente Prix SKU Disponibilité
100 mg
300,00 €
RL-4030.0100
<10 jour ouvrables
250 mg
500,00 €
RL-4030.0250
<10 jour ouvrables
500 mg
900,00 €
RL-4030.0500
<10 jour ouvrables
1 g
1 400,00 €
RL-4030.1000
sur demande
description

Azide-containing (suitable for Click-chemistry) linker for ð-Clamp-mediated (Phe-Cys-Pro-Phe) site-selective Cysteine conjugation. This concept was developed by Bradley L. Pentelute lab.


references

Enzymatic "click" ligation: selective cysteine modification in polypeptides enabled by promiscuous glutathione S-transferase; C. Zhang, A. M. Spokoyny, Y. Zou, M. D. Simon, B. L. Pentelute; Angew Chem Int Ed Engl. 2013; 52(52): 14001-5. https://doi.org/10.1002/anie.201306430

Convergent diversity-oriented side-chain macrocyclization scan for unprotected polypeptides; Y. Zou, A. M. Spokoyny, C. Zhang, M. D. Simon, H. Yu, Y.-S. Lin, B. L. Pentelute; Org. Biomol. Chem. 2014; 12: 566-573. https://doi.org/10.1039/C3OB42168F

ð-Clamp-mediated cysteine conjugation; C. Zhang, M. Welborn, T. Zhu, N. J. Yang, M. S. Santos, T. Van Voorhis, B. L. Pentelute; Nature Chem. 2016; 8, 120-128. https://doi.org/10.1038/nchem.2413

Site-Specific Small Molecule Labeling of an Internal Loop in JC Polyomavirus Pentamers Using the ð-Clamp-Mediated Cysteine Conjugation; J. A. Baccile, P. J. Voorhees, A. J. Chillo, M. Berry, R. Morgenstern, T. J. Schwertfeger, F. M. Rossi, C. D. S. Nelson; Chembiochem. 22(21); 3037-3041. https://doi.org/10.1002/cbic.202100188


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