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New
TG Rink-Trt (90µm)
Nom chimique: Fmoc-Rink amide-trityl TentaGel
- n° Art.:S309020
- Taille des particules:90 µm
- Chargement:0.18 - 0.25 mmol/g
from 140,00 €
description
TentaGel® resins consist of low cross-linked polystyrene on which poly(ethylene glycol) with a molecular weight of 3000 Da is grafted. The PEG spacer is attached to the polymer matrix via an ether bond, which shows high stability towards acid treatment and minimizes PEG leaching. The properties of TentaGel® resins are dominated by PEG, which solubilizes both hydrophobic and hydrophilic compounds, combined with high diffusion rates and excellent swelling in a wide range of solvents from e.g. toluene to water. TentaGel® resins are pressure stable and can be used in batch processes as well as under continuous flow conditions.
Treatment of this resin with diluted AcOH, TFE or mixtures of both in dichloromethane cleaves the trityl ester bond and releases the fully protected peptide amide. The C-terminus of the protected peptide amide is still masked by the Rink handle.
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