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Fmoc-L-Aza-OH (solv.)
Chemical name: (S)-2-(9-Fluorenylmethyloxycarbonylamino)-3-azidopropanoic acid, solvate with DIPE // Synonyms: Fmoc-L-Dap(N3)-OH, Fmoc-L-beta-azidoalanine, N-alpha-(9-Fluorenylmethyloxycarbonyl)-3-azido-L-alanine, Fmoc-Aza-OH (solv).
- Product code:FAA1820
- CAS No.:684270-46-0
- Formula:C18H16N4O4
- Storage temperature:2-8°C
- Molecular weight:352,34 g/mol
- Purity :min. 99%
- Enantiomeric Purity:min. 99,9%
from €72.00
description
Fmoc-Dap(N3) is incorporated into peptides that can be further selectively modified using Staudinger ligation or Click-chemistry. The azido-group, after incorporation into peptides, can be used as an IR probe to study local electrostatic environment in proteins.
references
Oh, Kwang-Im; Lee, Joo-Hyun; Joo, Cheonik; Han, Hogyu; Cho, Minhaeng Journal of Physical Chemistry B (2008), 112(33), 10352-10357.DOI:10.1021/jp801558k; Neupane, Lok Nath; Kim, Joung Min; Lohani, Chuda Raj; Lee, Keun-Hyeung Journal of Materials Chemistry (2012), 22(9), 4003-4008. DOI:10.1039/c2jm15664d; Empting, Martin; Avrutina, Olga; Meusinger, Reinhard; Fabritz, Sebastian; Reinwarth, Michael; Biesalski, Markus; Voigt, Stephan; Buntkowsky, Gerd; Kolmar, Harald Angewandte Chemie, International Edition (2011), 50(22), 5207-5211. DOI:10.1002/anie.201008142;
Inoue, Masaaki; Tamura, Takashi; Yoshimitsu, Yuji; Hohsaka, Takahiro; Watanabe, Takayoshi PCT Int. Appl. (2018), WO 2018174078 A1.
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