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Amino-Li Resin
Chemischer Name: Aminomethyl-poly(acryl amide) resin
- Art-Nr.:BR-1045
- Lagertemperatur:2-8°C
- Partikelgröße:45-55 mesh
- Beladung:0,4-0,6 mmol/g
Ab 80,00 €
description
Traditional supports such as Polystyrene and PEG resins face significant challenges, such as poor swellability and instability in acidic solutions. To address these issues, Li-Resin was developed, offering several advantages.
Li-Resin exhibits uniform swellability in most polar organic solvents and demonstrates robust chemical stability against strong acids and bases. This results in a stable resin bed during synthesis, ensuring better quality bio-molecules. Additionally, Li-Resin swells well in water and aqueous buffers, facilitating chemical manipulation and biochemical applications like on-resin screening and affinity chromatography.
Li-Resin consists of tiny sticks which make solvent flow through easily. Gentle shaking or mixing by bubbling Nitrogen through the suspension is recommended rather than vigorous mixing with a stirrer or a magnetic bar.
references
A Practical Peptide Synthesis Workflow Using Amino-Li-Resin; D. C. Akintayo, S. R. Manne, B. G. de la Torre, Y. Li, F. Albericio; Methods Protoc. 2022; 5(5): 72. https://doi.org/10.3390/mps5050072
Amino-Li-Resin—A Fiber Polyacrylamide Resin for Solid-Phase Peptide Synthesis; D. C. Akintayo, B. G. de la Torre, Y. Li, F. Albericio; Polymers 2022; 14(5): 928. https://doi.org/10.3390/polym14050928
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