H-L-Photo-Phe-OH

Chemischer Name: 4-(trifluoromethyldiazirin)-L-phenylalanine // Synonyme: H-Tdf-OH, (S)-2-amino-3-(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)propanoic acid, H-Photo-Phe-OH

Art-Nr.:HAA3490
CAS Nr.:92367-16-3
Lagertemperatur:-20°C
Formel:C₁₁H₁₀F₃N₃O₂
Molare Masse:273,21 g/mol

Ab 790,00 €

Gruppiert Produkte - Artikel
Anzahl	Verpackungsgröße	Preis	SKU	Warenverfügbarkeit
	50 mg	790,00 €	HAA3490.0050	11-20 Arbeitstage
	100 mg	1.100,00 €	HAA3490.0100	11-20 Arbeitstage
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references

Protein-Polymer Conjugation via Ligand Affinity and Photoactivation of Glutathione S-Transferase; En-Wei Lin, Natalie Boehnke, and Heather D. Maynard; Bioconjugate Chem. 2014; 25: 1902-1909; dx.doi.org/10.1021/bc500380r.

Cell-Based Proteome Profiling of Potential Dasatinib Targets by Use of Affinity-Based Probes; Haibin Shi, Chong-Jing Zhang, Grace Y. J. Chen, and Shao Q. Yao; J. Am. Chem. Soc. 2012; 134: 3001-3014; dx.doi.org/10.1021/ja208518u.

Probing Protein-Protein Interactions with a Genetically Encoded Photocrosslinking Amino Acid; Hui-wang Ai, Weijun Shen, Amit Sagi, Peng R. Chen, and Peter G. Schultz; ChemBioChem 2011; 12: 1854-1857; DOI: 10.1002/cbic.201100194

Proteome profiling reveals potential cellular targets of staurosporine using a clickable cell-permeable probe; Haibin Shi, Xiamin Cheng, Siu Kwan Sze and Shao Q. Yao; Chem. Commun. 2011; 47: 11306-11308; DOI: 10.1039/c1cc14824a.

Direct Interaction between an Allosteric Agonist Pepducin and the Chemokine Receptor CXCR4; Jay M. Janz, Yong Ren, Richard Looby, Manija A. Kazmi, Pallavi Sachdev, Amy Grunbeck, Lynn Haggis, Daniel Chinnapen, Amy Ying Lin, Christoph Seibert, Thomas McMurry, Kenneth E. Carlson, Tom W. Muir, Stephen Hunt III, and Thomas P. Sakmar; J. Am. Chem. Soc. 2011; 133: 15878-15881; dx.doi.org/10.1021/ja206661w.

Synthesis and application of photoproline - a photoactivatable derivative of proline; Benjamin Van der Meijden and John A. Robinson; ARKIVOC 2011 (vi) 130-136.,

Photo-crosslinking of proteins in intact cells reveals a dimeric structure of cyclooxygenase-2 and an inhibitor-sensitive oligomeric structure of microsomal prostaglandin E2 synthase-1; Pierre-Olivier Hétu, Marc Ouellet, Jean-Pierre Falgueyret, Chidambaram Ramachandran, Joel Robichaud, Robert Zamboni, Denis Riendeau; Archives of Biochemistry and Biophysics 2008; 477: 155-162; DOI: 10.1016/j.abb.2008.04.038.

Covalent Capture of Phospho-Dependent Protein Oligomerization by Site-Specific Incorporation of a Diazirine Photo-Cross-Linker; Miquel Vila-Perelló, Matthew R. Pratt, Frej Tulin, and Tom W. Muir; J. Am. Chem. Soc. 2007; 129: 8068-8069; DOI: 10.1021/ja072013j.

Photo-Leucine Incorporation Reveals the Target of a Cyclodepsipeptide Inhibitor of Cotranslational Translocation; Andrew L. MacKinnon, Jennifer L. Garrison, Ramanujan S. Hegde, and Jack Taunton; J. Am. Chem. Soc. 2007; 129: 14560-14561; DOI: 10.1021/ja076250y.

Synthesis of Photoactive Analogues of a Cystine Knot Trypsin Inhibitor Protein; Thomas Durek, Junliang Zhang, Chuan He, and Stephen B.H. Kent; Org. Lett. 2007; 9(26): 5497-5500; DOI: 10.1021/ol702461z.

Photo-leucine and photo-methionine allow identification of protein-protein interactions in living cells; Monika Suchanek, Anna Radzikowska, Christoph Thiele; Nature Methods 2005; 1-7; DOI: 10.1038/NMETH752.

Direct Interaction between an Allosteric Agonist Pepducin and the Chemokine Receptor CXCR4; J. M. Janz, Y. Ren, R. Looby, M. A. Kazmi, P. Sachdev, A. Grunbeck, L. Haggis, D. Chinnapen, A. Y. Lin, C. Seibert, T. McMurry, K. E. Carlson, T. W. Muir, S. Hunt and T. P. Sakmar; Journal of the American Chemical Society 2011; 133: 15878-15881. doi:10.1021/ja206661w

Protein–Polymer Conjugation via Ligand Affinity and Photoactivation of Glutathione S-Transferase; E.-W. Lin, N. Boehnke and H. D. Maynard; Bioconjugate Chemistry 2014; 25: 1902-1909. doi:10.1021/bc500380r

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis. James R. Hill, Avril A. B. Robertson; J. Med. Chem. 2018; 61: 6945−6963. DOI: 10.1021/acs.jmedchem.7b01561.