Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Währung
EUR
Schneller Kontakt
Bitte senden Sie mir mehr Informationen über
DBCO-PEG(4)-mal
Chemischer Name: Dibenzoazacyclooctyne-tetra(ethylene glycol)-maleimide // Synonyme: DBCO-PEG(4)-Maleimide
- Art-Nr.:RL-2500
- CAS Nr.:1480516-75-3
- Formel:C36H42N4O9
- Lagertemperatur:-20°C
- Molare Masse:674,74 g/mol
Ab 350,00 €
description
Cyclooctyne linker for conjugation via Diels-Alder-reaction, i.e. copper-free Click reaction with azides and tetrazines. The maleimide function will form thioethers with free thiols.
This PEG spacer has a length of 30 atoms or 29.7 A.
references
Simon et al.; Facile Double-Functionalization of Designed Ankyrin Repeat Proteins using Click and Thiol Chemistries. Bioconjugate Chem. 2012; 23(2): 279.
Zeng et al.; 64Cu Core-Labeled Nanoparticles with High Specific Activity via Metal-Free Click Chemistry. ACS Nano. 2012; 6(6): 5209.
Arumugam et al.; [18F]Azadibenzocyclooctyne ([18F]ADIBO): A biocompatible radioactive labeling synthon for peptides using catalyst free [3+2] cycloaddition. Bioorg. Med. Chem. Lett. 2011; 21: 6987.
Campbell-Verduyn et al.; Strain-Promoted Copper-Free Click Chemistry for 18F Radiolabeling of Bombesin. Angew. Chem. Int. Ed. 2011; 50: 11117.
Debets et al.; Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloaddition. Chem. Commun. 2010: 46: 97.
Benötigen Sie weitere Informationen über dieses Produkt?
kontaktieren Sie uns
Broschüren & Flyer
Produkte, die Sie auch interessieren könnten!
