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DBCO-SNAP
Synonyme: DBCO-BG, DBCO-Benzylguanine
- Art-Nr.:RL-4010
- Formel:C34H31N7O3
- Lagertemperatur:-20°C
- Molare Masse:585,67 g/mol
Ab 300,00 €
description
Alkyne conjugated benzylguanine (BG). The BG moiety reacts specifically and rapidly with the so-called SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation.
references
Reference:
Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors; J. Levitz, J. Broichhagen, P. Leippe, D. Konrad, D. Trauner, E. Y. Isacoff; PNAS 2017; 114(17): E3546-E3554. https://doi.org/10.1073/pnas.1619652114
Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand; J. Broichhagen, A. Damijonaitis, J. Levitz, K. R. Sokol, P. Leippe, D. Konrad, E. Y. Isacoff, D. Trauner; ACS Cent Sci. 2015; 1(7): 383-93. https://doi.org/10.1021/acscentsci.5b00260
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