For better service please confirm your country and language we detected.
Thank you very much for your interest in our products. All prices listed on our website are ex-works, Germany, and may attract customs duties when imported.
You may/will be contacted by the shipping company for additional documentation that may be required by the US Customs for clearance.
We offer you the convenience of buying through a local partner, Peptide Solutions LLC who can import the shipment as well as prepay the customs duties and brokerage on your behalf and provide the convenience of a domestic sale.
Continue to Iris Biotech GmbHSend request to US distributor
A carboxyl-reactive building block with enhanced solubility in aqueous media. Often a reagent of choice for the modification of biopolymers, peptides, and magnetic beads through carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters). A hydrophilic PEG3 spacer arm provides a long and flexible connection that minimizes steric hindrance involved with ligation to complementary tetrazine-containing molecules.
Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging; N. K. Devaraj, R. Weissleder, S. A. Hilderbrand; Bioconjugate Chemistry 2008; 19: 2297-2299. https://doi.org/10.1021/bc8004446.
Synthesis and Evaluation of a Series of 1,2,4,5-Tetrazines for Bioorthogonal Conjugation; M. R. Karver, R. Weissleder, S. A. Hilderbrand; Bioconjugate Chemistry 2011; 22: 2263-2270. https://doi.org/10.1021/bc200295y.
Peptidotriazoles on Solid Phase: [1,2,3]-Triazoles by Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions of Terminal Alkynes to Azides; C. W. Tornøe, C. Christensen, M. Meldal; The Journal of Organic Chemistry 2002; 67: 3057-3064. https://doi.org/10.1021/jo011148j.
A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes; V. V. Rostovtsev, L. G. Green, V. V. Fokin, K. B. Sharpless; Angewandte Chemie International Edition 2002; 41: 2596-2599. https://doi.org/10.1002/1521-3773(20020715)41:143.0.co;2-4.
Inverse electron demand Diels-Alder reactions in chemical biology; B. L. Oliveira, Z. Guo, G. J. L. Bernardes; Chem. Soc. Rev. 2017; 46: 4895-4950. https://doi.org/10.1039/C7CS00184C.
