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Blog | Page 54
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Custom Synthesis of Click-able compounds for Cu-free Click Conjugation
The presence of catalytic copper, limits the in vivo application of the Click this reaction for several reasons.
We offer custom synthesis of Strained Cyclooctynes and Substituted 1,2,4,5- Tetrazines as building blocks for fast Click reactions in the absence of any catalyst.
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Custom Synthesis of beta & gamma Amino Acids including Statine Analogues
GABA is a neurotransmitter in the central nervous system of mammals and its deficiency is associated with severe neurological disorders. Statine, a GABA analogue, occurs in several peptide APIs.
Derivatives of gamma-amino acid analogues are of continued vital interest for a variety of applications in medicinal chemistry.
We have a tool box available to offer a broad range of substituted gamma-amino acids and statines on custom synthesis basis.
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Life Science Baltics 2014
September 10th - 12th, 2014
LITEXPO, Vilnius
Vilnius, LithuaniaLife Sciences Baltics 2014 is the only international forum in the Baltics for world-class biotechnology, pharmaceutical and medical devices experts from all around the world. It provides a unique opportunity to explore the new horizons of partnerships, exchange ideas and seek progress through networking. Discover enormous potential and passion in the field of life sciences in Lithuania and the Baltics – the gateway to emerging markets.
- Discover state-of-the-art scientific infrastructure and investor-ready startups in the Baltics
- Meet Nobel prize winners, 800 key sector players and decision makers from more than 30 countries
- Learn about EU strategic directions and funding opportunities
- Tell the world about your discovery at the international conference, exhibition and networking events.
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BOSS XIV - 14th Belgian Organic Synthesis Symposium
July 13th - 18th, 2014
SOCRATE Auditorium
Louvain-la-Neuve, BelgiumThe BOSS-conference is a unique international symposium as it combines lectures delivered by established organic chemists as well as younger rising stars with two prestigious events: a lecture delivered by the recipient of the “Janssen Pharmaceutica Prize for Creativity in Organic Synthesis”, and the “Tetrahedron Chair”: a one-day course on a specific topic in organic synthesis.
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Preloaded Resins for Synthesis of Peptide Amides
Used for Efficient and Economic Bulk Synthesis of Peptide APIs:
A new technology is available with a set of new preloaded resins, which enable the synthesis of peptide amides WITHOUT ANY LINKER.
Amino acid amides, which bear a functional side chain, are immobilized on acid sensitive resins. This makes process development, small scale synthesis, bulk production and in-process control very easy.Find more technical details in our application for demonstration purposes with BIVALIRUDIN.
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Benzotriazole Amino Acids
Benzotriazol activated carboxylic acids:
- Fast reaction (within minutes) at room temperature with amines and other nucleophiles under addition of base (in both water and non- aqueous solvents).
- Stable to racemization when coupling with nucleophiles.
- High solubility in organic solvents like DMF and DCM.
- Stable in water.
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Luciferin for Research and Industry – from MG to KG Scale
In modern biotechnology there are numerous applications for the luminogenic luciferase assay. We supply luciferin from mg scale for research applications like monitoring of gene expression or tumor growth up to kg quantities for hygiene surveillance in food industry
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New: dPEG-Phospholipids for superior liposomes
Novel liposomes built of dPEG-Phospholipids with defined PEG chain length provide prolonged blood-circulation time and improved cellular uptake as administration carriers for drugs, delivering active molecules to the desired target.
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RICT 2014 - 50th International Conference on Medicinal Chemistry
July 2nd - 4th, 2014
Rouen’s Law Faculty
Rouen, Normandy, FranceThe “Golden Jubilee” of the “Rencontres Internationales de Chimie Thérapeutique” (RICT) will focus on “Interfacing Chemical Biology and Drug Discovery”. Chemical Biology can be defined as the use of chemical tools to unravel biological processes. The chemical approach to Biology may not only contribute a quantitative framework for the description (and prediction!) of complex biological events, but also tools for the generation of probes and binding molecules. Indeed, a part of the Congress will focus on experimental and theoretical approaches for the study of molecular interactions, exploring molecular space for the isolation of protein ligands and for the development of new drugs.
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14th Naples Workshop on Bioactive Peptides
June 12th - 14th, 2014
Centro Congressi of University of Naples "Frederico II"
Napoli, ItalyThe Workshop, designed to provide updated information and to critically discuss current trends on synthetic and conformational aspects of bioactive peptides, will deal in the 14th edition with the general subject: "The Renaissance era of Pepitdes in Drug Discovery".
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