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Fmoc-L-Asp(OBno)-OH
Nombre químico: N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-aspartic acid beta-(5-butylnon-5-yl) ester // Sinónimos: Fmoc-Asp(OBno)-OH, N-alpha-Fmoc-(O-5-(n-butyl)-non-5-yl)aspartic acid, (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-((5-butylnonan-5-yl)oxy)-4-oxobutanoic acid,Fmoc-Asp(OBno)-OH
- Nº Artículo:FAA8125
- Nº CAS:1799418-06-6
- Fórmula:C32H43NO6
- Storage temperature:-20°C
- Masa molecular:537,70 g/mol
from 430,00 €
description
An extremely effective derivative for minimizing aspartimide formation during Fmoc SPPS of Asp-containing peptides. The bulky OBno protecting group provides considerably more protection against the formation of aspartimide-related by-products than the commonly used OtBu and OMpe groups.
references
Preventing aspartimide formation in Fmoc SPPS of Asp-Gly containing peptides - practical aspects of new trialkylcarbinol based protecting groups. Raymond Behrendt, Simon Huber, Peter White; J. Pept. Sci. 2016; 22(2):, 92-97. DOI:10.1002/psc.2844
New t-butyl based aspartate protecting groups preventing aspartimide formation in Fmoc SPPS. Raymond Behrendt, Simon Huber, Roger Marti, Peter White. J. Pept. Sci. 2015; 21(8):, 680-687. DOI:10.1002/psc.2790
Patent EP 2 886 531 B1
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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