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Fmoc-L-Sec(Mob)-OPfp
Nombre químico: N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-4-methoxybenzyl selenocysteine pentafluorophenyl ester // Sinónimos: Fmoc-L-Sec(pMeOBzl)-OPfp, Fmoc-Sec(MBzl)-OPfp, Fmoc-L-Sec(Pmb)-OPfp, Fmoc-Sec(Mob)-OPfp, Fmoc-L-4-methoxybenzyl selenocysteine pentafluorophenyl ester, 2,3,4,5,6-pentafluorophenyl(2R)-2-({[(9H-fluor en-9-yl)methoxy]carbonyl}amino)-3-{[(4-methoxyphen
- Nº Artículo:FAA8760
- Nº CAS:939431-43-3
- Fórmula:C32H24F5NO5Se
- Storage temperature:-20°C
- Masa molecular:676,51 g/mol
- Pureza:min. 98%
- Pureza Enantiomérica:min. 99,7%
from 162,00 €
description
Isomeric purity >99.9%. Building block for the introduction of selenocysteine by SPPS. Peptides containing selenocysteine can be cleaved from the resin with simultaneous side-chain deprotection by treatment with 5% (v/v) water, 95% (v/v) trifluoroacetic acid (TFA), 0.4 M 2,2’-dithiobis(5-nitropyridine) (DTNP) for 7 min at 60 °C or 2 h at RT.
references
References:
Selenocysteine-Mediated Native Chemical Ligation; R. Quaderer, A. Sewing, D. Hilvert; Helv. Chim. Acta 2001; 84(5): 1197-1206; https://doi.org/10.1002/1522-2675(20010516)84:5<1197::AID-HLCA1197>3.0.CO;2-%23
Selenoglutathione: Efficient Oxidative Protein Folding by a Diselenide; J. Beld, K. J. Woycechowsky, D. Hilvert; Biochemistry 2007; 46(18): 5382-5390. https://doi.org/10.1021/bi700124p.
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Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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