Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
EUR
Contacto rápido
Por favor envíeme más información sobre
C14-[PGA(DIOL)]20-H
Nombre químico: (Tetradecylamine)-poly-L-glutamic acid(gamma-dihydroxypropylamide)acetamide
- Nº Artículo:PGA1890
- Storage temperature:-20°C
- Masa molecular:4000 Da
from A petición
description
Nucleic acids have emerged in recent years to yield promising drug candidates for a wide range of diseases, as also shown in terms of the development of the mRNA vaccine to fight the Covid-19 pandemic. As nucleic acids are not able to pass physiological barriers, novel tools for packing and delivery are required especially as the frequently used polyethylene glycol may lead to the generation of anti-PEG antibodies that may cause immunogenicity and allergic reactions. Iris Biotech offers a selection of innovative lipidated PSar and PGA-based polyamino acids for improved drug delivery.
references
Polysarcosine-Functionalized Lipid Nanoparticles for Therapeutic mRNA Delivery; S. Nogueira, A. Schlegel, K. Maxeiner, B. Weber, M. Barz, M. A. Schroer, C. E. Blanchet, D. Svergun, S. Ramishetti, D. Peer, P. Langguth, U. Sahin, H. Haas; ACS Appl. Nano Mater. 2020; 3(11): 10634-10645. https://doi.org/10.1021/acsanm.0c01834.
* Disclaimer
We refer to our general terms and conditions.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
¿Necesita más información sobre este producto?
ponerse en contacto
Folletos y volantes
¡Otros productos que también podrían interesarle!
