TBTA

Nombre químico: Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine

  • Nº Artículo:RL-2010
  • Nº CAS:510758-28-8
  • Fórmula:C30H30N10
  • Storage temperature:-20°C
  • Masa molecular:530,63 g/mol

from 300,00 €

Grouped product items
Cantidad Unidad de venta Precio Unidad de almacenamiento de stock (SKU) Disponibilidad
1 g
300,00 €
RL-2010.1000
<10 días laborables
5 g
720,00 €
RL-2010.5000
<10 días laborables
description

Tris(benzyltriazolylmethyl)amine (TBTA) is stabilizing copper(I) towards oxidation in solution by forming a complex and catalyzes effectively quantitative, regioselective Huisgen 1,3-dipolar cycloadditions between alkynes and azides (the so called 'click' cycloaddition reaction), in a variety of aqueous and organic solvents. In the literature, it has been gaining widespread use as a biochemical tool for the tagging of proteins and enzymes.

references

Polytriazoles as copper(I)-stabilizing ligands in catalysis; T. R. Chan, R. Hilgraf, K. B. Sharpless and V. V. Fokin; Org Lett 2004; 6: 2853-5. https://doi.org/10.1021/ol0493094

'Click' cycloaddition catalysts: copper(I) and copper(II) tris(triazolylmethyl)amine complexes; P. S. Donnelly, S. D. Zanatta, S. C. Zammit, J. M. White and S. J. Williams; Chem Commun (Camb) 2008: 2459-61. https://doi.org/10.1039/b719724a


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