Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
EUR
Contacto rápido
Por favor envíeme más información sobre
Halo-PEG(5)-azide
Nombre químico: 1-azido-21-chloro-3,6,9,12,15-pentaoxahenicosane // Sinónimos: Haloalkane Dehalogenase Ligand
- Nº Artículo:RL-3640
- Nº CAS:1261238-21-4
- Fórmula:C16H32ClN3O5
- Storage temperature:-20°C
- Masa molecular:381,90 g/mol
from 450,00 €
description
This compound is reported as HaloTag linker ligand for the synthesis of a fluorescent pH-sensitive dye. The HaloTag is a reporter protein whose sequence can easily be fused to a gene of interest. Once expressed, this reporter protein is designed to covalently bind ligands that are composed of two parts: a reactive linker that forms the bond with HaloTag protein and a functional moiety in the form of a fluorescent dye or affinity handle. In this case, the HaloTag linker ligand is suitable for further conjugation via Click chemistry.
references
Direct pH measurements by using subcellular targeting of 5(and 6-) carboxyseminaphthorhodafluor in mammalian cells; H. A. Benink, M. G. McDougall, D. H. Klaubert, G. V. Los; Biotechniques 2018; 47(3): 769-774. https://doi.org/10.2144/000113220.
Preparaion of purine derivatives for treating cancer; H. Arimoto, K. Itto, D. Takahashi, N. Cho, H. Nara, K. Shimokawa, O. Kenichiro, S. Taiichi, I. Shigekazu, N. Ishii; PCT Int. Appl. 2018; WO2018143403A1.
HaloTag technology: a versatile platform for biomedical applications; C. G. England, H. Luo and W. Cai; Bioconjug Chem 2015; 26: 975-86. https://doi.org/10.1021/acs.bioconjchem.5b00191.
HaloTag: a novel protein labeling technology for cell imaging and protein analysis; G. V. Los, L. P. Encell, M. G. McDougall, D. D. Hartzell, N. Karassina, C. Zimprich, M. G. Wood, R. Learish, R. F. Ohana, M. Urh, D. Simpson, J. Mendez, K. Zimmerman, P. Otto, G. Vidugiris, J. Zhu, A. Darzins, D. H. Klaubert, R. F. Bulleit and K. V. Wood; ACS Chem Biol 2008; 3: 373-382. https://doi.org/10.1021/cb800025k.
* Disclaimer
We refer to our general terms and conditions.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
¿Necesita más información sobre este producto?
ponerse en contacto
Related news
-
Ver másNews Linkerology Life Sciences Product FocusChoose your Taste – Functionalized Halo/Snap/Clip Substrates
The HaloTag®, SNAP-Tag® and CLIP-TagTM represent versatile tools for the specific, covalent attachment of in principle any molecule of
-
Ver másNews Linkerology Life Sciences Product Focus News Product of the month Linkerology Life SciencesPotM: Substrates for Fusion (Halo/Snap/Clip)-Tagged Proteins
-
Ver másNews Linkerology Life Sciences Product Focus News Product of the month Linkerology Life Sciences Product FocusReview – Product Highlights 2021
Folletos y volantes
¡Otros productos que también podrían interesarle!
