New

Fmoc-Glu(OtBu)-Val-Ala-PAB-PNP

Nom chimique: tert-butyl(S)-4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-(((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxopropan-2-yl)amino)-1-oxobutan-2-yl)amino)-5-oxo pentanoate

  • n° Art.:ADC1840
  • n° CAS:3034752-87-6
  • Formule:C46H51N5O12
  • Storage temperature:-20°C
  • Masse moléculaire:865,93 g/mol

from 500,00 €

Grouped product items
Nombre Unité de vente Prix SKU Disponibilité
100 mg
500,00 €
ADC1840.0100
sur demande
250 mg
1 000,00 €
ADC1840.0250
sur demande
New
description

Compared to the commonly used Val-Cit ADC linker, acidic tripeptide-based linkers such as Glu-Val-Cit provide enhanced hydrophilicity and serum stability. The introduced glutamic acid improves the linkers resistance to the carboxylesterase Cs1C and human neutrophil elastase (NE) preventing premature payload release and improving serum stability.

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