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Boc-L-Tyr(2-azidoethyl)-OH
Nom chimique: N-alpha-t-Butyloxycarbonyl-O-(2-azidoethyl)-L-tyrosine // Synonymes: Boc-O-(2-azidoethyl)-L-tyrosine, Boc-4-(2-azidoethoxy)-L-phenylalanine, Boc-Tyr(Azidoethyl)-OH, Boc-L-Tyr(Azidoethyl)-OH,(S)-3-(4-(2-azidoethoxy)phenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid, Boc-O-(2-azidoethyl)-L-Tyr-OH, Boc-Tyr(2-azidoeth
- n° Art.:BAA4650
- n° CAS:1434445-10-9
- Formule:C16H22N4O5
- Storage temperature:2-8°C
- Masse moléculaire:350,38 g/mol
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description
This unnatural Boc-protected Tyrosine derivative bears an azidoethyl substitution as reactive handle e.g. for biorthogonal conjugations, via a Cu(I)-catalyzed 1,3-dipolar Click cycloaddition with alkynes. Furthermore, azido-UAAs can be employed as IR reporters.
references
Structure-Based Design of Inhibitors Selective for Human Proteasome b2c or b2i Subunits; B.-T. Xin, E. M. Huber, G. de Bruin, W. Heinemeyer, E. Maurits, C. Espinal, Y. Du, M. Janssens, E. S. Weyburne, A. F. Kisselev, B. I. Florea, C. Driessen, G. A. van der Marel, M. Groll, H. S. Overkleeft; J. Med. Chem. 2019; 62(3): 1626-1642. https://doi.org/10.1021/acs.jmedchem.8b01884.
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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