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Fmoc-L-Tyr(2-azidoethyl)-OH
Nom chimique: N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-(2-azidoethyl)-L-tyrosine // Synonymes: Fmoc-4-(2-azidoethoxy)-L-phenylalanine, Fmoc-O-(2-azidoethyl)-L-tyrosine, Fmoc-4-(2-azidoethoxy)-L-phenylalanine, Fmoc-Tyr(Azidoethyl)-OH, Fmoc-L-Tyr(Azidoethyl)-OH,(S)-2-((((9H-fluoren-9-yl)methoxy )carbonyl)amino)-3-(4-(2-azidoethoxy)phenyl)propan
- n° Art.:FAA8535
- n° CAS:1454816-10-4
- Formule:C26H24N4O5
- Storage temperature:2-8°C
- Masse moléculaire:472,50 g/mol
- Pureté:min. 98%
- Pureté Énantiomérique:min. 99,7%
from 126,00 €
description
This unnatural Fmoc-protected Tyrosine derivative bears an azidoethyl substitution as reactive handle e.g. for biorthogonal conjugations, via a Cu(I)-catalyzed 1,3-dipolar Click cycloaddition with alkynes. Furthermore, azido-UAAs can be employed as IR reporters.
references
The Discovery of Macrocyclic XIAP Antagonists from a DNA-Programmed Chemistry Library, and Their Optimization To Give Lead Compounds with in Vivo Antitumor Activity; B. A. Seigal, W. H. Connors, A. Fraley, R. M. Borzilleri, P. H. Carter, S. L. Emanuel, J. Fargnoli, K. Kim, M. Lei, J. G. Naglich, M. E. Pokross, S. L. Posy, H. Shen, N. Surti, R. Talbott, Y. Zhang, N. K. Terrett; J. Med. Chem. 2015; 58(6): 2855-2861. https://doi.org/10.1021/jm501892g.
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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