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Building Blocks
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New Maillard Products for Peptide Synthesis and Analytics
Benefit of our latest Maillard Reaction Product additions! Use them as reference standard for quality control and food analysis or synthesize modified peptides for research studies.
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A Triazolecarbaldehyde for Selective N-Terminal Protein Modification
Looking for methods to selectively modify your peptide’s N-terminus? Discover triazolecarbaldehydes and benefit of mild reaction conditions, high yields, and compatibility with aqueous media.
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PotM: Furan-Crosslinking and 5HP2O as Maleimide Alternative
Game Changer for Protein Modification: Discover oxidation-induced furan crosslinking and 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones (5HP2Os) as stable alternative to maleimides.
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Hidden Champion – The Tetrahydropyranyl Protective Group
Tetrahydropyranyl (THP) is an excellent protective group for hydroxy and thiol moieties but rarely used in solid-phase peptide synthesis (SPPS). Discover its advantages, e.g., over O/StBu and Trt.
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Common Side Reactions in Fmoc Solid-Phase Peptide Synthesis
Collect information about the most common side reactions during Fmoc SPPS and how to avoid them! Choose your building blocks and conditions wisely to avoid unnecessary trouble!
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Bioisosteric Argininine Analogs
Same but different! Expand your possibilities for peptide modification and fine-tuning by implementing Nω-carbamoylated arginine building blocks as bioisosteric arginine analogs.
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Norbornenes – Will You Click Me?
Proposing norbornenes – strained, bicyclic alkenes for fast, copper-free, biocompatible click-conjugation with tetrazines. Read on for more details on applications and available products!
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PotM: About the Impact of Fluorinated Building Blocks
Clever Move - Add positive effects to your molecule by introducing the most electronegative element. Discover fluorinated building blocks as game changer for your lead development.
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Carboxymethyl Amino Acid Derivatives
Level up! Carboxymethyl-modified amino acid building blocks suitable for incorporation by solid-phase peptide synthesis. Learn more about available derivatives and their properties.
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Azobenzene Photoswitches
Engineer shape-shifting peptides, controllable by a laser as magic wand! In this newsletter, we’ll explore the possibilities of photo switchable building blocks based on azobenzene.
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